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פרופ' דרור מרחיים

יועץ ביחידה למחלות זיהומיות

כרטיס ביקור:

פרופסור במחלקה לרפואה פנימית, הפקולטה לרפואה ע"ש סאקלר, אוניברסיטת תל-אביב, תל-אביב. ראש היחידה למניעת זיהומים ומניעתן, המרכז הרפואי אסף הרופא, מרצה בכיר במחלקה לרפואה פנימית, הפקולטה לרפואה ע"ש סאקלר, אוניברסיטת תל-אביב, תל-אביב

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פרופ' דרור מרחיים - יועץ ביחידה למחלות זיהומיות

קורות חיים

מרפאה קלינית, המחלקה לרפואה, אוניברסיטת ויין סטייט, מישיגן, ארה"ב
11/2011 רופא בכיר, היחידה למחלות זיהומיות, המרכז הרפואי אסף הרופא, צריפין, ישראל
10/2012 מרצה בכיר, המחלקה לרפואה פנימית, הפקולטה לרפואה ע"ש סאקלר, אוניברסיטת תל-אביב, תל-אביב
11/2013 מנהל תחום מניעת זיהום ומניעתן, היחידה למחלות זיהומיות, המרכז הרפואי אסף הרופא, צריפין, ישראל
10/2017 ראש היחידה למניעת זיהומים ומניעתן, המרכז הרפואי אסף הרופא, צריפין, ישראל
04/2018 פרופסור במחלקה לרפואה פנימית, הפקולטה לרפואה ע"ש סאקלר, אוניברסיטת תל-אביב, תל-אביב

ניסיון תעסוקתי

2002-2006 מתמחה במחלקה פנימית א ', המרכז הרפואי אסף הרופא, צריפין, ישראל
2007-2009 עמית קליני, היחידה למחלות זיהומיות, המרכז הרפואי תל-אביב סוראסקי, תל-אביב, ישראל
2009-2011 עמית קליני, חוקר מחקר, היחידה למניעת זיהומים ומניעתן, אחיות אנטי-מיקרוביאליות ואפידמיולוגיה של בית החולים, מרכז רפואי דטרויט, אוניברסיטת ויין סטייט, מישיגן, ארה"ב

פרסומים רפואיים – (רשימה חלקית)

Marchaim D, Hallak M, Gortzak-Uzan L, Peled N, Riesenberg K, Schlaeffer F. Cell-wall proteins of group B streptococcus and low incidence of neonatal disease in southern Israel. Journal of Reproductive Medicine 2003; 48:697-702.
2. Marchaim D, Hallak M, Gortzak-Uzan L, Peled N, Riesenberg K, Schlaeffer F. Risk factors for carriage of group B streptococcus in southern Israel. Israel Medical Association Journal 2003; 5:646-648.
3. Bisharat N, Jones N, Marchaim D, Block C, Harding RM, Yagupsky P, Peto T, Crook DW. Population structure of group B streptococcus from a low incidence region for invasive neonatal disease. Microbiology 2005; 151:1875-1881.
4. Marchaim D, Lazarovitch Z, Efrati S, Dishy V, Weissgarten J, Bouldur I, Zaidenstein R. Serious consequences to the use of cephalosporins as the first line of antimicrobial therapy administered in hemodialysis units. Nephron Clinical Practice 2005; 101:58-64.
5. Marchaim D, Efrati S, Melamed R, Gortzak-Uzan L, Riesenberg K, Zaidenstein R, Schlaeffer F. Clonal variability of group B streptococcus among different groups of carriers from southern Israel. European Journal of Clinical Microbiology and Infectious Diseases 2006; 25:443-48.
6. Marchaim D, Navon-Venezia S, Schwartz D, Tarabeia J, Fefer I, Schwaber MJ, Carmeli Y. Surveillance Cultures and Duration of Carriage of Multi-Drug-Resistant Acinetobacter baumannii. Journal of Clinical Microbiology 2007; 45:1551-55.
7. Marchaim D, Navon-Venezia S, Leavitt A, Chmelnitsky I, Schwaber MJ, Carmeli Y. Molecular and Epidemiologic Study of Polyclonal Outbreaks of Multidrug Resistant Acinetobacter baumannii Infection in an Israeli Hospital. Infection Control and Hospital Epidemiology 2007; 28:945-50.
8. Marchaim D, Navon-Venezia S, Schwaber MJ, Lidgi S, Carmeli Y. Isolation of imipenem-resistant Enterobacter species: emergence of KPC-2 carbapenemase, molecular characterization, epidemiology, and outcomes. Antimicrobial Agents and Chemotherapy 2008; 52:1413-18.
9. Marchaim D, Zaidenstein R, Lazarovitch T, Karpuch Y, Ziv T, Weinberger M. Epidemiology of bacteremia episodes in a single center: increase in Gram-negative isolates, antibiotics resistance, and patient age. European Journal of Clinical Microbiology and Infectious Diseases 2008; 27:1045–51.
10. Efrati S, Sadetzki S, Zaretsky M, Kimiagar I, Rosenblum R, Marchaim D, Berman S, Bar-Haim A, Abu Hamad R, Feigenzon M, Chetrit A, Yassky D, Weissgarten J, Bass A. Carotid atherosclerotic disease following childhood scalp irradiation. Atherosclerosis 2009; 204:556-60.
11. Marchaim D, Kaye KS, Fowler V, Chawla V, Golan Y, Karchmer AW, Carmeli Y. Case-control study to identify factors associated with mortality among patients with methicillin-resistant Staphylococcus aureus bacteremia. Clinical Microbiology and Infection 2010; 16:747-52.
12. Reddy T, Chopra T, Marchaim D, Pogue J, Alangaden G, Salimnia H, Dhar S, Kaye KS. Trends in antimicrobial resistance of Acinetobacter baumannii isolates from a metropolitan Detroit health system. Antimicrobial Agents and Chemotherapy 2010; 54:2235:38.
13. Kaye KS, Marchaim D, Klock K, Bentley L. Suction Regulators: A potential vector for hospital acquired pathogens. Infection Control and Hospital Epidemiology 2010; 31:772-74.
14. Dhar S, Tansek R, Toftey B, Dzeikan B, Chevalier TC, Bohlinger CG, Fitch M, Flanagan E, Chopra T, Marchaim D, Kaye KS. Observer bias in hand hygiene compliance reporting. Infection Control and Hospital Epidemiology 2010; 31:869-70.
15. Marchaim D, Gottesman T, Schwartz O, Korem M, Maor Y, Rahav G, Karplus R, Lazarovitch T, Braun E, Sprecher H, Lachish T, Wiener-Well Y, Alon D, Chowers M, Ciobotaro P, Bardenstein R, Paz A, Potasman I, Giladi M, Schechner V, Schwaber MJ, Lidji S, Carmeli Y. National multi-center study of predictors and outcomes of bacteremia upon hospital admission caused by Enterobacteriaceae producing extended-spectrum β-lactamases. Antimicrobial Agents and Chemotherapy 2010; 54: 5099-104.

Marchaim D, Chopra T, Pogue JM, Perez F, Hujer AM, Rudin S, Endimiani A, Navon-Venezia S, Hothi J, Slim J, Blunden C, Shango M, Lephart PR, Salimnia H, Reid D, Moshos J, Hafeez W, Bheemreddy S, Chen TY, Dhar S, Bonomo RA, Kaye KS. Outbreak of colistin-resistant, carbapenem-resistant Klebsiella pneumoniae in metropolitan Detroit, Michigan. Antimicrobial Agents and Chemotherapy 2011; 55: 593-599.
17. Kaye KS, Marchaim D, Chen TY, Chopra T, Anderson DJ, Choi Y, Sloane R, Schmader KE. Predictors of Nosocomial Bloodstream Infections in Older Adults. Journal of the American Geriatrics Society 2011; 59:622-627.
18. Chopra T, Binienda J, Mohammed M, Shyamraj R, Long P, Bach D, Carlton C, Peters S, Lephart PR, Alangaden G, Dhar S, Marchaim D, Schreiber M, Kaye KS. A Practical Method for Surveillance of Novel H1N1 Influenza Using Automated Hospital Data. Infection Control and Hospital Epidemiology 2011; 32:700-702.
19. Marchaim D, Chopra T, Perez F, Hayakawa K, Lephart PR, Bheemreddy S, Blunden C, Hujer AM, Rudin S, Shango M, Campbell M, Varkey J, Slim J, Ahmad F, Patel D, Chen TY, Pogue JM, Salimnia H, Dhar S, Bonomo RA, Kaye KS. Outcomes and genetic relatedness of carbapenem-resistant Enterobacteriaceae at Detroit Medical Center. Infection Control and Hospital Epidemiology 2011; 32: 861-71.
20. Hayakawa K, Marchaim D, Vidaillac C, Lephart PR, Pogue JM, Sunkara B, Kotra H, Hasan A, Shango M,Yerramalla Y, Osunlana AM, Chopra T, Dhar S, Salimnia H, Rybak MJ, Kaye KS. Growing Prevalence of Vancomycin-resistant Enterococcus faecalis in the region with the highest prevalence of vancomycin-resistant Staphylococcus aureus. Infection Control and Hospital Epidemiology 2011; 32:922-4.
21. Schechner V, Gottesman T, Schwartz O, Korem M, Maor Y, Rahav G, Karplus R, Lazarovitch T, Braun E, Finkelstein R, Lachish T, Wiener-Well Y, Alon D, Chowers M, Bardenstein R, Zimhony O, Paz A, Potasman I, Giladi M, Schwaber MJ, Lidji S, Hochman M, Marchaim D, Carmeli Y. Pseudomonas aeruginosa bacteremia upon hospital admission: Risk factors for mortality and influence of inadequate empirical antimicrobial therapy. Diagnostic Microbiology and Infectious Disease 2011; 71:38-45.
22. Pogue JM, Lee J, Marchaim D, Yee V, Zhao JJ, Chopra T, Lephart PR, Kaye KS. Incidence of and risk factors for colistin-associated nephrotoxicity in a large academic health-system. Clinical Infectious Diseases 2011; 53:879-84.
23. Sunkara B, Bheemreddy S, Lorber B, Lephart PR, Hayakawa K, Sobel JD, Kaye KS, Marchaim D. Group B Streptococcus infections in non-pregnant adults: the role of immunosuppression. International Journal of Infectious Diseases 2012; 16:e182-6.
24. Collins VL, Marchaim D, Pogue JM, Moshos J, Bheemreddy S, Sunkara B, Shallal A, Chugh N, Eiseler S, Bhargava P, Blunden C, Lephart PR, Irfan Memon B, Hayakawa K, Abreu-Lanfranco O, Chopra T, Munoz-Price LS, Carmeli Y, Kaye KS. Efficacy of Ertapenem for Treatment of Bloodstream Infections Caused by Extended-Spectrum-β-Lactamase-Producing Enterobacteriaceae. Antimicrobial Agents and Chemotherapy 2012; 56:2173-7.
25. Hayakawa K, Marchaim D, Martin ET, Tiwari N, Sunkara B, Yousuf A, Pulluru H, Kotra H, Hasan A, Bheemreddy S, Sheth P, Lee D, Kamatam S, Bathina P, Nanjireddy P, Chalana IK, Patel S, Kumar S, Vahia A, Ku K, Yee V, Swan J, Pogue JM, Lephart PR, Rybak MJ, Kaye KS. Comparison of the clinical characteristics and outcomes associated with vancomycin-resistant Enterococcus faecalis and vancomycin-resistant E. faecium bacteremia. Antimicrobial Agents and Chemotherapy 2012; 56:2452-8.
26. Chopra T, Marchaim D, Veltman J, Johnson P, Zhao JJ, Tansek R, Hatahet D, Chaudhry K, Pogue JM, Rahbar H, Chen TY, Truong T, Rodriguez V, Ellsworth J, Bernabela L, Bhargava A, Yousuf A, Alangaden G, Kaye KS. Impact of Cefepime Therapy on Mortality among Patients with Bloodstream Infections Caused by Extended-Spectrum-beta-Lactamase-Producing Klebsiella pneumoniae and Escherichia coli. Antimicrobial Agents and Chemotherapy 2012; 56:3936-42.
27. Marchaim D, Chopra T, Bhargava A, Bogan C, Dhar S, Hayakawa K, Pogue JM, Bheemreddy S, Blunden C, Shango M, Swan J, Lephart PR, Perez F, Bonomo RA, Kaye KS.Recent exposure to antimicrobials and carbapenem-resistant Enterobacteriaceae: the role of antimicrobial stewardship. Infection Control and Hospital Epidemiology 2012; 33:817-30.
28. Marchaim D, Sunkara B, Lephart PR, Mynatt RP, Zhao JJ, Bheemreddy S, Hayakawa K, Chopra T, Dhar S, Kaye KS. Extended-spectrum β-lactamase producers reported as “susceptible” to piperacillin/tazobactam, cefepime, and cefuroxime, in the era of lowered break-points and no confirmatory tests. Infection Control and Hospital Epidemiology 2012; 33:853-5.
29. Judge T, Pogue JM, Marchaim D, Ho K, Kamatam S, Parveen S, Tiwari N, Nanjireddy P, Bheemreddy S, Biedron C, Lepakshi Reddy SM, Khammam V, Chalana IK, Tumma RS, Collins V, Yousuf A, Lephart, PR, Martin ET, Rybak MJ, Kaye KS, Hayakawa K. Epidemiology of Vancomycin-resistant enterococci with reduced susceptibility to daptomycin. Infection Control and Hospital Epidemiology 2012; 33:1250-54.
30. Hayakawa K, Marchaim D, Pogue JM, Sarwan K, Lephart PR, Sobel JD, Kaye KS. Growing Prevalence of Providencia stuartii associated with the increased usage of colistin at a tertiary healthcare center. International Journal of Infectious Diseases 2012; 16:e646-48.
31. Marchaim D, Taylor AR, Abreu-Lanfranco O, Bheemreddy S, Sunkara B, Moshos J, Hayakawa K, Chopra T, Panda S, Pogue JM, Lephart PR, Dhar S, Kaye KS. Hospital Bath Basins are Frequently Contaminated with Multi-Drug Resistant Human Pathogens. American Journal of Infection Control 2012; 40:562-64.
32. Marchaim D, Chopra T, Bogan C, Bheemreddy S, Sengstock D, Jagarlamudi R, Malani A, Lemanek L, Moshos J, Lephart PR, Ku K, Hasan A, Lee J, Khandker N, Blunden C, Geffert SF, Moody M, Hiro R, Wang Y, Ahmed F, Mohammadi T, Faruque O, Patel D, Pogue JM, Hayakawa K, Dhar S, Kaye KS. The burden of multidrug-resistant organisms on tertiary hospitals posed by patients with recent stays in long-term acute care facilities. American Journal of Infection Control 2012; 40:760-65.
33. Chopra T, Marchaim D, Lynch Y, Kosmidis C, Zhao JJ, Dhar S, Gheyara N, Turner D, Gulish D, Wood M, Alangaden G, Kaye KS. Epidemiology and Outcomes Associated with Surgical Site Infection Following Bariatric Surgery. American Journal of Infection Control 2012; 40:815-19.
34. Marchaim D, Perez F, Lee J, Bheemreddy S, Hujer AM, Rudin S, Hayakawa K, Lephart PR, Blunden C, Shango M, Campbell ML, Varkey J, Manickam P, Patel D, Pogue JM, Chopra T, Martin ET, Dhar S, Bonomo RA, Kaye KS. “Swimming in resistance”: co-colonization with carbapenem-resistant Enterobacteriaceae and Acinetobacter baumannii or Pseudomonas aeruginosa. American Journal of Infection Control 2012; 40:830-35.
35. Ku K, Pogue JM, Moshos J, Bheemreddy S, Wang Y, Bhargava A, Campbell M, Khandker N, Lephart PR, Chopra T, Hayakawa K, Martin ET, Abreu-Lanfranco O, Dhar S, Kaye KS, Marchaim D. Retrospective evaluation of colistin versus

tigecycline for the treatment of Acinetobacter baumannii and/or carbapenem-resistant Enterobacteriaceae infections. American Journal of Infection Control 2012; 40:983-7.
36. Hayakawa K, Marchaim D, Pogue JM, Ho K, Parveen S, Nanjireddy P, Sunkara B, Singla M, Jagadeesh KK, Moshos JA, Bommarito S, Mroue R, Farhat M, Obeid T, Chaudhry A,Vadlamudi G, Lephart PR, Martin ET, Rybak MJ, Kaye KS. Predictors and outcomes of linezolid-resistant vancomycin-resistant Enterococcus: a case-case-control study. American Journal of Infection Control 2012; 40:e261-63.
37. Marchaim D, Lemanek L, Bheemreddy S, Kaye KS, Sobel JD. Fluconazole-resistant Candida albicans vulvovaginitis. Obstetrics and Gynecology 2012; 120:1407-14.
38. Campbell ML, Marchaim D, Pogue JM, Sunkara B, Bheemreddy S, Chugh N, Poona A, Wilson MN, Moshos J, Ku K, Singh K, Chopra T, Hayakawa K, Martin ET, Lephart PR, Rybak MJ, Kaye KS. Treatment of methicillin-resistant Staphylococcus aureus infections with a minimal inhibitory concentration of 2μg/mL to vancomycin: old (trimethoprim/sulfamethoxazole) versus new (daptomycin or linezolid) agents. Annals of Pharmacotherapy 2012; 46:1587-97.
39. Hayakawa K, Marchaim D, Palla M, Mahesh Gudur U, Pulluru H, Bathina P, Alshabani K, Govindavarjhulla A, Mallad A, Reddy Abbadi D,Chowdary D, Kakarlapudi H, Guddati H, Das M, Kannekanti N, Vemuri P, Doddamani R, Rakesh Mundra VR, Reddy Guddeti R, Policherla R, Bai S, Lohithaswa S, Prasad Shashidharan S, Chidurala S, Diviti S, Sukayogula K, Joseph M, Pogue JM, Lephart PR, Martin ET, Rybak MJ, Kaye KS. Epidemiology of vancomycin-resistant Enterococcus faecalis: a case-case-control study. Antimicrobial Agents

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